We are pleased to share our new publication in Nature Structural & Molecular Biology, entitled: “Characterizing dynamics of productive dynein stepping by MINFLUX.”

This collaborative study uses MINFLUX microscopy to follow the microtubule-binding domain of dynein with nanometer precision and submillisecond time resolution. The results reveal a brief backward displacement before productive steps and connect ATP turnover to forward movement, clarifying how this molecular motor walks along microtubules.

Citation
Slivka, J., Gleave-Hanford, E. S., Golcuk, M., Wijewardena, D. P., Canty, J. T., Selvin, P. R., Gur, M., Carter, A. P., Yildiz, A. (2026). Characterizing dynamics of productive dynein stepping by MINFLUX. Nature Structural & Molecular Biology, 33(9), 1324-1331. (IF: 10.1; 5-year IF: 11.3)

View the publication
https://www.nature.com/articles/s41594-026-01873-w